NCT04780230

Non-invasive Brain Stimulation to Enhance Treatment of Dysarthria Post-stroke

Modulation of Primary Motor Cortex to Enhance Treatment of Dysarthria Post-stroke

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: The Hong Kong Polytechnic University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The proposed study aims to determine if transcranial direct current stimulation can enhance the effect of speech therapy in post-stroke patients with dysarthria.

Detailed description

A total of 60 Cantonese-speaking post-stroke patients who are suffering from dysarthria will be recruited and randomly divided into real tDCS and sham groups. All the participants will receive individualized speech therapy based on the results of their speech assessment. For the real tDCS group, an anodal high-definition tDCS of 2 milliamperes (mA) lasting for 20 minutes will be delivered to the orofacial area of the primary motor cortex (SM1) during speech therapy. For the sham tDCS group, stimulation given during speech therapy will only last for 30 seconds in order to cause a similar sensation on the scalp as the real stimulation group. There will be a total of 10 daily sessions during a 2-week period.

Conditions

• Dysarthria
• Stroke

Interventions

Type	Name	Description
DEVICE	tDCS active	An anodal high-definition tDCS of 2 mA lasting for 20 minutes will be delivered to the orofacial area of the primary motor cortex (SM1) during speech therapy.
DEVICE	tDCS sham	An anodal high-definition tDCS of 2 mA lasting for 30 seconds will be delivered to the orofacial area of the primary motor cortex (SM1) during speech therapy.

Timeline

• Start date: 2020-12-21
• Primary completion: 2023-11-30
• Completion: 2023-11-30
• First posted: 2021-03-03
• Last updated: 2024-01-18

Locations

1 site across 1 country: Hong Kong