NCT04779281

Effects of Probiotics and Nutritional Status on Exercise-Induced Symptoms, and Endurance Performance in Ultra-Endurance Athletes

Effects of Nutritional Status and Probiotics on Exercise-Related Clinical and Gastrointestinal Symptoms and Endurance Performance in Ultra-Endurance Athletes

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Istanbul Medeniyet University · Academic / Other
• Sex: All
• Age: 20 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

Ultra-endurance athletes have been commonly endured extreme conditions during races and training sessions, resulting in exercise-associated clinical symptoms, including gastrointestinal symptoms, dehydration, and elevated oxidative stress. Although these alterations adversely affect sports performance and well-being, there is no certain treatment or consensus on alleviating the exercise-associated clinical symptoms in ultra-endurance athletes. The objective of this study is to determine the effects of oral rehydration salts supplemented with Lactobacillus Rhamnosus GG on exercise-induced gastrointestinal problems, dehydration and oxidative stress in ultra-endurance athletes. Additionally, we aimed to assess the exercise-induced alterations in oxidative stress determined by applying an acute strenuous exercise protocol ((a cycle ergometer (45 min at 65%VO2max) immediately followed by a treadmill test (75% VO2max to exhaustion)) before and after the supplementation period.

Conditions

• Ultra-endurance Athletes With Gastrointestinal Symptoms

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Oral Rehydration Salts supplemented with L. Rhamnosus GG	A supplement containing sodium chloride, trisodium citrate, potassium chloride, dextrose, Lactobacillus Rhamnosus GG ATC53103 HN019 strain and fructooligosaccharides
DIETARY_SUPPLEMENT	Oral Rehydration Salts only	A supplement containing sodium chloride, trisodium citrate, potassium chloride, dextrose, microcrystalline cellulose

Timeline

• Start date: 2018-09-01
• Primary completion: 2019-05-15
• Completion: 2019-05-15
• First posted: 2021-03-03
• Last updated: 2021-03-03

Locations

1 site across 1 country: Turkey (Türkiye)