NCT04777747

The Role of Lactate in Viral and Bacterial Infection

The Role of Lactate From Viral to Bacterial Infection

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 400 (actual)
• Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Academic / Other
• Sex: All
• Age: 1 Minute – 18 Years
• Healthy volunteers: Not accepted

Summary

Acute upper respiratory tract infection(AURI) is common in children, and viral infection is the main cause. However, several children with viral infection are easy to suffer from secondary bacterial infection, and the mechanism is unclear.

Detailed description

Lactate is an important molecule in the spread and metastasis of tumor by suppressing the innate immune response. As is known, the immune system is not mature in children and it is reverse related to the age of children. An reasonable hypothesis is that the lactate is a independent risk factor in the children with viral infection progress to bacterial infection. Here, our aim is to test the hypothesis.

Conditions

• Viral Infection
• Bacterial Infections
• Lactate Blood Increase

Interventions

Type	Name	Description
OTHER	viral infection	a child is infected by virus only
OTHER	viral and bacterial infection	a child is infected by virus and progress to bacterial infection

Timeline

• Start date: 2021-01-01
• Primary completion: 2023-03-31
• Completion: 2023-03-31
• First posted: 2021-03-02
• Last updated: 2023-05-01

Locations

1 site across 1 country: China