NCT04775381

Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation

Study of Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation

• Status: Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Hôpital NOVO · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This prospective study evalue the inflence of pre operative vit D3 administration on post operative hypocalcemia in patients undergoing Total thyroidectomy

Detailed description

Thyroidectomy is a frequent procedure. This surgery is well known but not devoid of risks. The most common postoperative complication is transitory hypocalcemia. Some studies have reported that preoperative vitamin D deficiency (VDD) is a risk factor for hypocalcemia after total thyroidectomy (TT) in patients with non toxic multinodular goiter or graves's disease. Although the association between VVD and postoperative hypocalcemia in thyroid cancer patients undergoing TT plus central compartment neck dissection (CCND) remains unclear. This prospective study evalue the inflence of pre operative vit D3 administration on post operative hypocalcemia in patients undergoing TT.

Conditions

• Hypocalcemia

Interventions

Type	Name	Description
DRUG	Vitamin D	Patients will receive a cholecalciferol supplementation added to a fruit juice.

Timeline

• Start date: 2021-06-30
• Primary completion: 2025-12-01
• Completion: 2026-03-01
• First posted: 2021-03-01
• Last updated: 2025-01-20

Locations

6 sites across 1 country: France