NCT04774757

Systemic Therapy Sequenced Isolated PALND for mCRC

Curative Systemic Therapy Sequenced Radical Surgery for Synchronous Isolated Paraaortic Lymph Node Metastasis of Colorectal Cancer

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 39 (estimated)
• Sponsor: First Affiliated Hospital of Zhejiang University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The study aims to estimate the efficacy and safety of systemic therapy sequenced radical surgery in treating patients with synchronous isolated para-aortic lymph node metastasis of colorectal cancer.

Detailed description

Patients with synchrnous isolated para-aortic lymph node metastasis of colorectal cancer receiving systemtic therapy (at most two lines), radiologically assessed efficacious, and assessed by MDT that are potential to reach no evidence of disease (NED) were included in our trial. All included patients receive para-aortic lymph node dissection.

Conditions

• Synchronous Isolated Para-aortic Lymph Node Metastasis
• Colorectal Cancer

Interventions

Type	Name	Description
PROCEDURE	Para-aortic lymph node dissection	Para-aortic lymph node dissection was defined as the dissection of para-aortic lymph nodes located below renal vein and above the bifurcation of iliac artery.

Timeline

• Start date: 2021-03-10
• Primary completion: 2023-03-01
• Completion: 2026-03-01
• First posted: 2021-03-01
• Last updated: 2021-10-11

Locations

1 site across 1 country: China