NCT04771923

Tranexamic Acid Versus Adrenaline for Controlling Iatrogenic Endobronchial Bleeding

Tranexamic Acid Versus Adrenaline for Controlling Iatrogenic Endobronchial Bleeding: a Double Blind, Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 130 (actual)
• Sponsor: Clinical Hospital Centre Zagreb · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Endobronchial bleeding is a relatively common complication of diagnostic bronchoscopy. Both tranexamic acid and adrenaline are used topically for the control of endobronchial bleeding. The aim of this study is to compare the efficacy of tranexamic acid with adrenaline in controlling iatrogenic endobronchial bleeding after diagnostic bronchoscopy.

Conditions

• Bleeding
• Hemoptysis

Interventions

Type	Name	Description
DRUG	Tranexamic acid	Topical instillation of tranexamic acid up to 3x. If bleeding is not controlled patients crossover to adrenaline.
DRUG	Adrenaline	Topical instillation of adrenaline up to 3x. If bleeding is not controlled patients crossover to tranexamic acid.

Timeline

• Start date: 2021-02-22
• Primary completion: 2022-02-04
• Completion: 2022-02-04
• First posted: 2021-02-25
• Last updated: 2022-02-24

Locations

1 site across 1 country: Croatia