Trials / Completed
CompletedNCT04768829
Antifungal Potential of Moringa Olifera Against Otomycosis
Antifungal Potential of Moringa Olifera-loaded Nanoparticles Against Otomycosis; Preparation, Characterization, and Clinical Evaluation
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 10 (actual)
- Sponsor
- Deraya University · Academic / Other
- Sex
- All
- Age
- 20 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
patients with Otomycosis were recognized by an ENT specialist. 20 patients were distributed randomly into two groups. The first group will be treated with Nystatin ear drops twice daily. The second group will be treated with Moringa ear drops. patients will be examined endoscopically by the ENT specialist. patient's swabs will be isolated and analyzed by ELISA.
Detailed description
Inclusion criteria: (1) Otomycosis . Exclusion criteria: 1. tympanic membrane perforation; 2. concurrent immune suppression, 3. and concurrent bacterial infection.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Moringa oleifera leaf 10mg/100ml | ear drops |
| DRUG | Ear Drop | plain ear drop formulation without moringa |
Timeline
- Start date
- 2021-02-18
- Primary completion
- 2021-09-15
- Completion
- 2021-12-01
- First posted
- 2021-02-24
- Last updated
- 2022-03-09
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04768829. Inclusion in this directory is not an endorsement.