NCT04768751

Acute Kidney Injury as a Risk Factor for Myocardial Injury and Ventricular Dysfunction

Assessment of Acute Kidney Injury as a Risk Factor for Myocardial Injury and Ventricular Systolic Dysfunction After Non-Cardiac Surgery in Critical Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 520 (actual)
• Sponsor: South Egypt Cancer Institute · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Acute kidney injury (AKI) is classically described as an abrupt or rapidly reversible reduction in the excretion of nitrogenous waste products, including urea, nitrogen and creatinine. Acute kidney injury definition emphasizes on the filtration function of the kidney, a measure that is unique and easily and routinely measured . Acute kidney injury is associated with significantly increased resource utilization and health care costs. Major adverse cardiac events (MACE) after non cardiac surgery are a leading cause of morbidity and mortality. The reported incidence of postoperative myocardial infarction (POMI) among patients undergoing non cardiac surgery is between 3% and 6%.

Conditions

• Acute Kidney Injury
• Ventricular Dysfunction
• Myocardium; Injury

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	kidney assessment	Urea, BUN, and Creatinine BLOOD LEVELS

Timeline

• Start date: 2019-03-05
• Primary completion: 2020-08-20
• Completion: 2020-08-30
• First posted: 2021-02-24
• Last updated: 2021-02-24

Locations

1 site across 1 country: Egypt