NCT04766151

Nitrate Use to Obtain Radial Spasm Embarrassment (NURSE - TTS Trial)

A Randomised, Double-blind, Parallel Group, Efficacy and Safety Study of Transdermal Patch Nitroglycerin in the Prevention of Coronary Artery Spasm, During Coronary Angiography/ Angioplasty (NURSE-TTS - Nitrate Use to Obtain Radial Spasm Embarrassment)

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: 424 General Military Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Transradial cardiac catheterization and percutaneous coronary intervention are increasingly being performed worldwide in elective and emergency procedures, with many centres adopting the transradial route as their first choice of arterial access. One of the most common complications encountered during transradial procedures is radial artery spasm. The aim of this study is to evaluate the Efficacy and Safety of the use of transdermal Glyceryl trinitrate patches applied to skin before cardiac catheterization to prevent the occurrence of radial artery spasm during transradial access cardiac catheterization.

Conditions

• Radial Artery Spasm

Interventions

Type	Name	Description
DRUG	Transdermal glyceryl trinitrate 10mg patches	Transdermal patches applied to skin 30 minutes before cardiac catheterization
DRUG	Placebo patches	Transdermal placebo patches applied to skin 30 minutes before cardiac catheterization

Timeline

• Start date: 2021-01-01
• Primary completion: 2021-12-31
• Completion: 2022-06-30
• First posted: 2021-02-23
• Last updated: 2021-02-23

Locations

1 site across 1 country: Greece