NCT04762914

Observing the Perioperative Effects of Prehabilitation in Colorectal Cancer Patients

Observing the Perioperative Effects of Prehabilitation in Colorectal Cancer

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 52 (actual)
• Sponsor: Medway Primary Care Trust · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Quality Improvement Project to evaluate how prehabilitation can be incorporated into our colorectal cancer pathway and assess its clinical benefits.

Detailed description

The aim was to evaluate how prehabilitation (PH) can be incorporated into our colorectal cancer pathway and assess its clinical benefits. Patients underwent PH (exercise, nutrition and psychological support) before resection of colorectal carcinoma in a DGH over fourteen months. Patients were matched by operation, age, sex and ASA to non-prehabilitation (NPH) patients using a prospectively maintained database. Length of stay (LoS) and complication rate and 90-day readmission rates were compared using Wilcoxon and McNemar's methods. Prehabilitation significantly improved peak VO2 and AT. This corresponds to a reduction in predicted 30-day mortality. Despite a higher Charlson index LoS was unchanged suggesting prehabilitation may permit safe resection in comorbid patients.

Conditions

• Colon Cancer

Interventions

Type	Name	Description
OTHER	Prehabilitation	Prehabilitation is a multimodal and multidisciplinary person-centred perioperative approach involving supervised exercise training, nutritional education, management of polypharmacy and psychological advice.

Timeline

• Start date: 2018-09-01
• Primary completion: 2019-12-31
• Completion: 2019-12-31
• First posted: 2021-02-21
• Last updated: 2021-02-21

Locations

1 site across 1 country: United Kingdom