NCT04762615

Impact of Underlying Renal Disease and Immunosuppressive Regimen on Ovarian Reserve in Renal Patients

Impact of the Immunosuppressive Treatment, X-ray Exposition and Renal Pathology on Ovarian Reserve in Young Women

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 153 (actual)
• Sponsor: Wroclaw Medical University · Academic / Other
• Sex: Female
• Age: 18 Years – 44 Years
• Healthy volunteers: Not accepted

Summary

Aging, renal pathology (eg SLE, ADPKD), X-ray exposition and pharmacological treatments, especially previous strong immunosuppression, may negatively influence the ovarian reserve in childbearing age women. Anti-Müllerian hormone (AMH) is regarded as biomarker for ovarian reserve. Every female with renal disease regularly menstruating that met exclusion criteria could have participated. The aim was to assess ovarian reserve in female patients with normal menstrual cycle and kidney disease, including kidney transplant recipients.

Conditions

• Anti-Mullerian Hormone Deficiency
• Immunosuppression
• Ovarian Reserve
• X-rays; Effects

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	AMH level measurement	AMH level measurement using ELISA test from blood samples

Timeline

• Start date: 2018-06-01
• Primary completion: 2019-11-10
• Completion: 2020-12-01
• First posted: 2021-02-21
• Last updated: 2021-02-21

Locations

1 site across 1 country: Poland