Clinical Trials Directory

Trials / Terminated

TerminatedNCT04757883

Immunological Follow-up After SARS CoV2 Vaccination in Kidney Transplant Recipients

Immunological Follow-up After COVID 19 Vaccination in Kidney Transplant Recipients

Status
Terminated
Phase
Study type
Observational
Enrollment
37 (actual)
Sponsor
University Hospital, Strasbourg, France · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The investigators goal is to assess the vaccine response of kidney transplant patients following vaccination against SARS-CoV-2. The study population will be derived from cohorts of kidney transplant patients who have been transplanted for more than 3 months and have no contraindications to vaccination. These patients will be vaccinated as part of routine care with a CoV-2 SARS vaccine licensed in France. In this cohort, the investigators wish to study the post-vaccination humoral response by assaying neutralizing antibodies against SARS CoV-2 and the specific cellular response of SARS Cov-2 by quantiferon and in vitro lymphocyte stimulation assays.

Conditions

Interventions

TypeNameDescription
OTHERStudy of the synthesis of antibodies directed against SARSBetween 5 mL and 45 mL of additional blood will be collected to study the synthesis of antibodies against CoV-2 SARS and to investigate whether specialised immune cells also show an effective response against the virus.

Timeline

Start date
2021-02-02
Primary completion
2024-11-01
Completion
2024-11-01
First posted
2021-02-17
Last updated
2025-08-19

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT04757883. Inclusion in this directory is not an endorsement.