NCT04757727

Gynecological Follow-up of Patients With Dystrophic Epidermolysis Bullosa (EBD)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 27 (actual)
• Sponsor: Centre Hospitalier Universitaire de Nice · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: —

Summary

Dystrophic epidermolysis bullosa is a rare genetic pathology resulting in fragility of the skin and mucous membranes, causing bubbles and wounds following trauma. Scarring is pathological with a tendency to retraction. The gynecological and in particular the vulvovaginal mucous membranes can be affected but no description of any series is available in the literature. Likewise, some of these patients have a sexual and obstetrical life, despite sometimes-severe damage, but again no specific data is available. The investitigator thus wish to carry out a non-interventional multicenter prospective descriptive study. Better knowledge of gynecological semiology in patients with EBD will allow better adaptation of gynecological follow-up, screening for STDs and gynecological cancers, as well as possible specific complications. This study would eventually allow the draw up of recommendations for our gynecologist / obstetrician colleagues.

Conditions

• Dystrophic Epidermolysis Bullosa

Interventions

Type	Name	Description
OTHER	Decriptive study of EDB	data on EDB will be register

Timeline

• Start date: 2021-01-01
• Primary completion: 2021-09-30
• Completion: 2021-12-30
• First posted: 2021-02-17
• Last updated: 2025-04-03

Locations

2 sites across 1 country: France