NCT04755712

Comparison of Two Analgesic Strategies After Scheduled Caesarean

Comparison of Two Analgesic Strategies After Scheduled Caesarean : Block of the Lumbar Region With Ropivacaine Versus Intrathecal Morphine

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 104 (actual)
• Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To demonstrate the superiority of square lumbar block to ropivacaine compared to intrathecal morphine in the efficacy of postoperative analgesia following scheduled caesarean.

Detailed description

Interventional, comparative, randomized, controlled study versus reference therapeutic strategy, in 2 parallel groups, double-blind (patient and evaluator), single-center, aiming to demonstrate the superiority of ropivacaine in square lumbar block versus intrathecal morphine, on the efficacy of post-operative analgesia, following a scheduled caesarean.

Conditions

• Analgesia

Interventions

Type	Name	Description
DRUG	Rachianesthesia	Administration of different anesthesia drugs in accordance with the courant practice (mixture of bupivacaine and sufentanil)
DRUG	Sodium Chloride Injection	Subcutaneous injection of Sodium chloride at the usual quadratum lumburum block 2 (QLB2) injection site under ultrasound ("sham-QLB2").
DRUG	Morphine	Morphine via pump (patient controlled analgesia)

Timeline

• Start date: 2021-03-22
• Primary completion: 2022-10-12
• Completion: 2022-10-12
• First posted: 2021-02-16
• Last updated: 2024-08-05

Locations

1 site across 1 country: France