Trials / Completed
CompletedNCT04753775
RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF ENEMA ALOE VERA GEL IN ACTIVE ULCERATIVE PROCTOSIGMOIDITIS.
RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF ENEMA ALOE VERA GEL FOR ACHIVING REMISSION IN ACTIVE ULCERATIVE PROCTOSIGMOIDITIS.
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 44 (actual)
- Sponsor
- Ospedale Sandro Pertini, Roma · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Aloe vera is used for the treatment of inflammatory bowel disease (IBD), but no data are present in regard the gel formulation as topical therapy in active ulcerative colitis.
Detailed description
44 ulcerative colitis (UC) patients were enrolled and randomly allocated to treatment for 4 weeks with oral mesalazine (800 mg three times daily) and enema (60 ml aloe vera gel) 1/day (n = 22, Group A) or enema (60 ml placebo) (n = 22, Group B).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Aloe vera gel |
Timeline
- Start date
- 2010-03-10
- Primary completion
- 2010-04-10
- Completion
- 2010-05-10
- First posted
- 2021-02-15
- Last updated
- 2021-02-15
Source: ClinicalTrials.gov record NCT04753775. Inclusion in this directory is not an endorsement.