NCT04753736

Immunophenotypage of RIF and RM Patients and Intrauterine Administration of PBMC

Intrauterine Administration and Immunophenotyping of Autologous Peripheral Blood Mononuclear Cells in Patients With Repeated Implantation Failures During Undergoing in Vitro Fertilization Treatment

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Fertilys · Industry
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to identify a systemic immunological profile specific to patients with recurrent implantation failures (RIF) or miscarriages (RM) through blood immunophenotyping on the day of ovulation. This study also aims to determine whether the intrauterine administration of 5 million peripheral blood monocluear cells increases implantation and pregnancy rates in patients with RIF and decreases the risk of miscarriages in patients with RM, compared to what has already been published in the scientific literature

Conditions

• Infertility, Female

Interventions

Type	Name	Description
PROCEDURE	Intrauterine administration of hCG-activated peripheral blood mononuclear cells	Intrauterine administration of hCG-activated peripheral blood mononuclear cells

Timeline

• Start date: 2021-09-24
• Primary completion: 2021-11-01
• Completion: 2021-11-01
• First posted: 2021-02-15
• Last updated: 2023-09-18

Locations

1 site across 1 country: Canada