Clinical Trials Directory

Trials / Unknown

UnknownNCT04752865

Effects of Cytotoxic Chemotherapy and PARP Inhibition on the Genomic Contexture of Ovarian Cancer

Status
Unknown
Phase
Study type
Observational
Enrollment
50 (estimated)
Sponsor
Hellenic Cooperative Oncology Group · Academic / Other
Sex
Female
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

EFFECTS OF CYTOTOXIC CHEMOTHERAPY AND PARP INHIBITION ON THE GENOMIC CONTEXTURE OF OVARIAN CANCER: TR\_NACT\_OV/17 In order to approach the above open questions, ultimately aiming in understanding the effects of cancer drugs on tumor biology and hence in selecting the proper drugs for the patients in the context of Precision Medicine, the objective of this study is to study the genomic characteristics of ovarian tumors before and after treatment with classic neoadjuvant chemotherapy (NACT) and with the more recently approved PARP inhibitor olaparib.

Conditions

Timeline

Start date
2018-02-09
Primary completion
2023-12-01
Completion
2024-06-01
First posted
2021-02-12
Last updated
2023-03-01

Locations

1 site across 1 country: Greece

Source: ClinicalTrials.gov record NCT04752865. Inclusion in this directory is not an endorsement.