Clinical Trials Directory

Trials / Completed

CompletedNCT04752644

Phase 2a Study of MVA-BN-RSV Vaccination and RSV Challenge in Healthy Adults

A Phase 2a, Randomised, Double-Blinded, Placebo-Controlled Study to Assess the Safety, Immunogenicity and Efficacy of the Recombinant MVA-BN®-RSV Vaccine Against Respiratory Syncytial Virus Infection in the Virus Challenge Model in Healthy Adult Participants

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
73 (actual)
Sponsor
Bavarian Nordic · Industry
Sex
All
Age
18 Years – 50 Years
Healthy volunteers
Accepted

Summary

A Phase 2a, Randomised, Double-Blinded, Placebo-Controlled Study to Assess the Safety, Immunogenicity and Efficacy of the Recombinant MVA-BN®-RSV Vaccine against Respiratory Syncytial Virus Infection in the Virus Challenge Model in Healthy Adult Participants

Conditions

Interventions

TypeNameDescription
BIOLOGICALMVA-mBN294BMVA-BN-RSV (nominal titre 5 x10\*8 Inf.U per 0.5 mL) as intramuscular injections. Liquid frozen suspension, single dose of 0.5ml.
DRUGPlaceboTBS (Placebo) as intramuscular injections (0.5ml)

Timeline

Start date
2021-02-22
Primary completion
2021-06-17
Completion
2021-11-02
First posted
2021-02-12
Last updated
2023-07-21

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT04752644. Inclusion in this directory is not an endorsement.