Trials / Unknown
UnknownNCT04750135
Assessment of Metformin as Adjuvant Therapy in Patients With Ulcerative Colitis
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- National Hepatology & Tropical Medicine Research Institute · Other Government
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
Brief Summary: This is a randomized, controlled study evaluating metformin tablets administered daily for 8 weeks. The purpose of the study is to evaluate the efficacy and safety of metformin in the treatment of mild to moderately active ulcerative colitis. Disease activity will be measured using Mayo score for ulcerative colitis activity. Calculation of the score requires patients to undergo colonoscopy at the start of the study and at week 8.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | metformin 500 mg TID Oral Tablet | biguanides derivatives |
| DRUG | Placebo | Placebo |
Timeline
- Start date
- 2021-02-07
- Primary completion
- 2021-06-01
- Completion
- 2021-06-01
- First posted
- 2021-02-11
- Last updated
- 2021-02-11
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04750135. Inclusion in this directory is not an endorsement.