Trials / Unknown
UnknownNCT04749407
Biomarkers of Stage III Locally Advanced Unresectable Non-small-cell Lung Cancer
Dynamic Biomarkers of Immune Microenvironment for Stage III Locally Advanced Unresectable Non-small-cell Lung Cancer
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- First People's Hospital of Hangzhou · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to dynamically monitor the expression profile status of peripheral blood mononuclear cells (PBMC) and the changes in circulating tumor DNA (ctDNA) levels in patients with stage III locally advanced unresectable non-small-cell lung cancer(NSCLC) after concurrent chemoradiotherapy or sequential chemoradiotherapy, and to explore biomarkers related to the immune microenvironment and the optimal time point for immunotherapy after chemoradiotherapy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | biomarker detection | PBMC and ctDNA analysis |
Timeline
- Start date
- 2021-02-01
- Primary completion
- 2022-07-01
- Completion
- 2022-12-01
- First posted
- 2021-02-11
- Last updated
- 2021-02-11
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04749407. Inclusion in this directory is not an endorsement.