NCT04748263

Eye Gaze Strategies During Facial Emotion Recognition in Neurodegenerative Diseases: Links With Neuropsychiatric Disorders (EYE-ToM Study)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 70 (actual)
• Sponsor: Centre Hospitalier Princesse Grace · Academic / Other
• Sex: All
• Age: 45 Years
• Healthy volunteers: —

Summary

It is commonly admitted that social cognition impairment, like deficit in facial emotion recognition or misinterpretation of others' intentions (Theory of Mind), are associated with social behavior disorders. This kind of disorders are observed in Fronto-Temporal Dementia (FTD), Alzheimer's Dementia (AD) and Parkinson's Disease (PD), with severe deficits in FTD and lighter deficits in AD and PD. One explanation might be that patients apply inappropriate visual exploration strategies to decode emotions and intentions of others. This study aims to test this hypothesis and further to analyse whether different patterns emerge from these pathologies.

Conditions

• Alzheimer's Dementia
• Parkinson Disease(PD)
• Fronto-Temporal Dementia

Interventions

Type	Name	Description
OTHER	No intervention. Only survey and normal use of eye-tracking	The study is conducted in accordance with usual practices of eye-tracking and neuropsychological evaluations carried out at the Center Rainier III. Eye-Tracker® is used at the Centre Rainier III since August 2014. It is a non-invasive device for eye movements recording, allowing doctors and researchers to measure standard parameters related to eye movements. Developed by the Eye Brain Company (France), this is a Class IIa medical device, CE marking, according to Annexe IX of the directive 93/42/CE.

Timeline

• Start date: 2015-07-01
• Primary completion: 2019-12-01
• Completion: 2020-11-01
• First posted: 2021-02-10
• Last updated: 2021-02-10