NCT04745715

Genomic Study in Non-small Cell Lung Cancer Brain Metastasis

Genomic Analysis in Surgically Treated NSCLC Brain Metastasis Based on Neurosurgical Perspectives

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 110 (actual)
• Sponsor: National Cheng-Kung University Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The investigators collected the data from the investigators' center between January 2011 and October 2020. The study included all non-small cell lung cancer patients with surgically excised brain metastasis. The investigators analysis the correlation of gene mutation and the disease course.

Detailed description

The investigators collected the data from from the investigators' center between January 2011 and October 2020. The study included all non-small cell lung cancer patients with surgically excised brain metastasis. The investigators analysis the correlation of gene mutation and the disease course. The investigators use Kaplan-Meier regression to analyze the overall survival, and the difference between the groups was calculated using log rank test. Cox proportional hazards method was used to create the regression model and estimate the hazard ratios.

Conditions

• NSCLC Stage IV
• Brain Metastases

Interventions

Type	Name	Description
PROCEDURE	craniectomy	craniectomy outcomes and survival

Timeline

• Start date: 2011-01-01
• Primary completion: 2020-10-31
• Completion: 2022-10-31
• First posted: 2021-02-09
• Last updated: 2023-04-04

Locations

1 site across 1 country: Taiwan