NCT04744935

Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Christopher Zachary · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Accepted

Summary

Optical coherence tomography guided laser treatment of basal cell carcinoma

Detailed description

The purpose of this pilot study is to examine the treatment basal cell carcinoma (BCC) with laser technology under the guidance of optical coherence tomography imaging (OCT). The laser modality that we plan to use is the long-pulse Nd:YAG 1064nm laser, which is a non-ablative laser already shown to effectively treat BCC. Laser treatment of BCC has limited precedent in the literature, but the addition of OCT has the opportunity to enhance outcomes by better targeting the treatment and permitting more precise monitoring of clearance. We propose to use OCT imaging to guide the laser treatment to achieve optimal efficacy with minimized side-effects.

Conditions

• Basal Cell Carcinoma
• Superficial Basal Cell Carcinoma
• Nodular Basal Cell Carcinoma

Interventions

Type	Name	Description
DEVICE	1064 nm long-pulse Nd:YAG laser	BCC lesion will be treated with long-pulse 1064 laser, with surface temperature monitored by infrared camera.

Timeline

• Start date: 2021-01-13
• Primary completion: 2027-02-17
• Completion: 2027-02-17
• First posted: 2021-02-09
• Last updated: 2026-03-24

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study