NCT04743154

In-hospital Versus After-discharge Complete Revascularization

In-hospital Versus After-discharge Complete Revascularization in STEMI Patients With Multivessel Disease.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 250 (actual)
• Sponsor: Hospital General Universitario de Valencia · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Patients with STEMI and multivessel disease in whom the culprit lesion has been successfully revascularized during prmimary PCI, will be randomized to in-hospital or after-discharge complete revascularization. The purpose of this study is to evaluate the impact of these two different strategies in terms of hospital stay.

Detailed description

STEMI patients with mutivessel disease are, after successful primary angioplasty, randomized 1:1 ratio to either in-hospital complete revascularization or after-discharge complete revascularization strategy. Eligible non-culprit coronary arteries must be \>2.0 mm in diameter and at the discretion of the operator suitable for PCI. Only arteries with angiographically stenoses ≥70% or between ≥50% and \<70 in proximal segments can be randomized. Patients in the in-hospital revascularization group will undergo to non-culprit percutaneous coronary intervention (PCI) at least 24 hours after ST-segment elevation myocardial infarction. On the other hand, patients in the after-discharge group will undergo to non-culprit PCI within 4-6 weeks after STEMI.

Conditions

• STEMI - ST Elevation Myocardial Infarction
• Multivessel Coronary Artery Disease

Interventions

Type	Name	Description
OTHER	In-hospital nonculprit-lesions percutaneous coronary intervention (PCI)	To perform percutaneous coronary intervention of non-culprit vessels in a staged procedure during index admission.
OTHER	After-discharge nonculprit-lesions percutaneous coronary intervention (PCI)	To perform percutaneous coronary intervention of non-culprit vessels in a staged procedure after hospital discharge.

Timeline

• Start date: 2018-01-20
• Primary completion: 2021-11-25
• Completion: 2022-12-21
• First posted: 2021-02-08
• Last updated: 2023-04-24

Locations

1 site across 1 country: Spain