NCT04742439

Individualizing tDCS Dose

Testing the Effects of Individualized and 4mA tDCS

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Transcranial direct current stimulation (tDCS) is a noninvasive method of modulating brain activity and has therapeutic potential in many neurological and psychiatric conditions. However, unlike every current FDA-approved form of brain stimulation, there is no method of individualizing stimulation dose. In this study, a method of individualizing tDCS dose on behavioral outcomes and whether this could help to improve the consistency and magnitude of the stimulation effects will be tested.

Conditions

• tDCS
• Motor Function

Interventions

Type	Name	Description
DEVICE	Sham transcranial direct current stimulation	Participants will receive 30 seconds of ramp up and down stimulation at the start and end of the 20 minute stimulation period.
DEVICE	Individualized transcranial direct current stimulation	Participants will receive 20 minutes of transcranial direct current stimulation (tDCS) at the individualized dose (maximum of 4mA).
DEVICE	2mA transcranial direct current stimulation	Participants will receive 20 minutes of transcranial direct current stimulation (tDCS) at a 2mA dose.
DEVICE	4mA transcranial direct current stimulation	Participants will receive 20 minutes of transcranial direct current stimulation (tDCS) at a 4mA dose.

Timeline

• Start date: 2024-12-02
• Primary completion: 2024-12-02
• Completion: 2024-12-02
• First posted: 2021-02-08
• Last updated: 2025-11-06

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study