NCT04742140

Magnesium Sulphate Injection in Treatment of Myofascial Trigger Points

Magnesium Sulphate Injection in Treatment of Myofascial Trigger Points in Masseter Muscle

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 180 (actual)
• Sponsor: Fayoum University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective, single- center, randomized (1:1) clinical trial comparing the effectiveness of magnesium sulphate injections in treatment of myofascial trigger points in the masseter muscle versus the saline injection.

Detailed description

The proposal presents the magnesium sulphate (MgSO4) as a possible injection treatment for TrPs. The MgSO4 prevents the release of pre-synaptic acetylcholine from neuromuscular and sympathetic junctions that could explain the ability of the MgSO4 to relax the muscle and reduce pain Specific aim: evaluate the effectiveness of magnesium sulphate injections in treatment of myofascial trigger points in the masseter muscle versus the saline injection. Hypothesis: the injection of masseter muscle trigger points with magnesium sulphate is more effective than saline injection in pain relief.

Conditions

• Trigger Point Pain, Myofascial

Interventions

Type	Name	Description
DRUG	Magnesium sulfate	each patient injected 0.5ml in each TrPs of magnesium sulphate according to the treatment group by the same operator
DRUG	Saline	each patient injected 0.5ml in each TrPs of saline according to the treatment group by the same operator

Timeline

• Start date: 2021-02-20
• Primary completion: 2021-08-20
• Completion: 2021-09-01
• First posted: 2021-02-05
• Last updated: 2021-12-07

Locations

1 site across 1 country: Egypt