NCT04735939

Chronotherapy for Radiotherapy of Glioma

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 80 (estimated)
• Sponsor: General Hospital of Ningxia Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study aims to determine if there is any difference in the efficacy of radiotherapy for glioma outcomes in the morning or in the evening. The study team believes that there may be a benefit to taking the radiotherapy at a certain time of day. To test this theory the study asks participants who are already taking radiotherapy for glioma consistently at either the morning or in the evening based on when they currently take their radiotherapy. There will be this study visits where the participant will be asked to fill in questionnaires related to their neurological symptoms, their sleep habits, sleep quality, survival situation, and general health information followed by a blood draw.

Detailed description

The objective of this study is to determine whether the timing of radiotherapy to treat glioma has an effect on patient outcomes. Primary objective: Determine whether there is a difference in outcomes seen when patients are assigned to take their radiotherapy at either a morning time or evening time. The Investigator hypothesize that administration time of radiotherapy during the day can affect the clinical outcomes in glioma patients. Specific Aims Include: * Determine whether morning vs. evening dosing radiotherapy could affect the survival time of glioma patients. * Determine whether morning vs. evening dosing radiotherapy could affect the KPS score of glioma patients. * Determine whether morning vs. evening dosing radiotherapy could affect the cognitive function of glioma patients.

Conditions

• To Determine Whether the Timing of Radiotherapy Has an Effect on Patient Outcomes

Interventions

Type	Name	Description
RADIATION	radiotherapy	Determine whether there is a difference in outcomes seen when patients are assigned to take their radiotherapy at either a morning time or evening time.

Timeline

• Start date: 2021-02-01
• Primary completion: 2021-12-31
• Completion: 2021-12-31
• First posted: 2021-02-03
• Last updated: 2021-02-03

Locations

1 site across 1 country: China