Trials / Active Not Recruiting
Active Not RecruitingNCT04734158
CORNEAL EPITHELIAL MAPPING IN DIABETICS
EVALUATION OF CORNEAL EPITHELIAL THICKNESS MAPPING IN DIABETIC PATIENTS USING ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY AND ITS CORRELATION TO MACULAR THICKNESS
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 153 (estimated)
- Sponsor
- Minia University · Academic / Other
- Sex
- All
- Age
- 40 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
The corneal epithelium is the outermost layer that covers the front of the eye; it not only functions as a barrier that blocks the passage of foreign material, but also plays an important role in maintaining high optical quality. The stem cells in the basal layer of the limbal epithelium hold a physiological significance in the renewal and metabolism of corneal epithelium, particularly under stressful situations.
Detailed description
The cornea in diabetic patients suffers from cellular dysfunction and dysfunctional repairal mechanisms, which include recurrent erosions, delayed wound healing, ulcers, and edema. In addition and undoubtedly related to epithelial dysfunction, alterations in epithelial basement membrane occur.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | corneal imaging | corneal imaging using AS-OCT |
Timeline
- Start date
- 2019-08-12
- Primary completion
- 2024-12-31
- Completion
- 2025-12-31
- First posted
- 2021-02-02
- Last updated
- 2024-04-11
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04734158. Inclusion in this directory is not an endorsement.