Trials / Completed
CompletedNCT04732442
Changes in Inflammatory Response After Immunonutrition Compared to Standard Nutrition in Colorectal Cancer Tissue
Changes in Inflammatory Response After Immunonutrition Compared to Standard Nutritional Support in Colorectal Cancer Tissue - Randomized Controlled Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- Jagiellonian University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
It is Randomized Controlled Trial, in which investigators will estimate the impact of the use of immunonutrition support compared to standard nutritional support in the preoperative period in patients with colorectal cancer.
Detailed description
The first choice of treatment in colorectal cancer is surgery. Nutritional support in form of oral nutritional supplements (ONS) in the preoperative period is widely accepted in reducing the incidence of perioperative complications and immunonutrition is generally recommended. However, there is little clinical data regarding the impact of such treatment on a tumor biology. Investigators want to perform Randomized Controlled Trial to explore the impact of the use of immunonutrition in relation to standard nutritional support in the preoperative period on alternating the expression of inflammatory response cytokines expression and leukocytes infiltration in tumor tissue in patients operated for colorectal cancer.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Immunonutrition | Impact Oral® Nestle, Switzerland |
| DIETARY_SUPPLEMENT | Standard Oral Nutritional Support | Fortimel Compact Protein® Nutricia, United Kingdom |
Timeline
- Start date
- 2017-11-01
- Primary completion
- 2018-11-30
- Completion
- 2019-01-30
- First posted
- 2021-02-01
- Last updated
- 2021-02-01
Locations
1 site across 1 country: Poland
Source: ClinicalTrials.gov record NCT04732442. Inclusion in this directory is not an endorsement.