NCT04731610

Randomized, Multicenter, Phase III Trial to Assess Conformal Post-operative Radiotherapy vs. Surveillance After Complete Resection of Stage II/III Thymoma (RADIO-RYTHMIC-01)

Randomized, Multicenter, Phase III Trial to Assess Conformal Post-operative Radiotherapy vs. Surveillance After Complete Resection of Stage II/III Thymoma

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 314 (estimated)
• Sponsor: Institut Curie · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of the study : to compare the Recurrence-Free survival (RFS) between arms. RFS is defined as time from randomisation to the first recurrence (either local-regional or distant) or death of any cause.

Conditions

• Thymoma Malignant Recurrent

Interventions

Type	Name	Description
OTHER	Radiotherapy	postoperative radiotherapy after complete resection of thymoma
OTHER	Surveillance after resection	Surveillance after tumour resection

Timeline

• Start date: 2021-12-28
• Primary completion: 2031-12-28
• Completion: 2032-12-28
• First posted: 2021-02-01
• Last updated: 2026-02-02

Locations

20 sites across 1 country: France