Trials / Unknown
UnknownNCT04730089
Epidural Block Impairs HPV During One-lung Ventilation: an EIT- Based Prospective Observation Study
Epidural Block Impairs Hypoxic Pulmonary Vasoconstriction During One-lung Ventilation: an Electrical Impedance Tomography- Based Prospective Observation Study
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- Shanghai Zhongshan Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Define the effect of epidural block on HPV by EIT.
Detailed description
Epidural block may affect the physiological mechanism of hypoxic pulmonary vasoconstriction, which is still poorly understood. Electrical impedance tomography might be helpful in establishing the hypoxemia etiology at bedside via combining regional ventilation and perfusion information.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Electrical impedance tomography | A bolus of 10ml 10% NaCl was injected during a respiratory pause (≥10s) through the central venous catheter.The results of arterial blood gas analysis and the data of EIT were collected before the first prone session (time baseline), the end of prone positioning (time P). |
Timeline
- Start date
- 2020-08-01
- Primary completion
- 2022-07-31
- Completion
- 2022-07-31
- First posted
- 2021-01-29
- Last updated
- 2021-01-29
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04730089. Inclusion in this directory is not an endorsement.