NCT04724070

PRecision Oncology CUhk pRogrammE (PRO-CURE)

Comprehensive Precision Oncology Program at The Chinese University of Hong Kong

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Brigette Ma · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The main aim of this project is to establish an innovative model of a comprehensive precision oncology platform to help individualizing drug therapy for patients with advanced cancers at The Chinese University of Hong Kong. The other objectives include to optimize the genomic matching and access of patients with unique cancer subtypes to the relevant clinical trials of novel therapies, and to construct a personalized drug screening platform for individuals using novel cancer models established from patient-derived cancer cells and tissues. Other objectives include to investigate the utility and feasibility of genomic sequencing using circulating tumor DNA(ctDNA), and to establish a biobank of tumor tissues derived from patients with unique cancer subtypes.

Conditions

• Gastrointestinal Cancers

Interventions

Type	Name	Description
GENETIC	NGS, PDO/PDX establishment	Patients' tumor specimens will be collected for next generation sequencing, PDO/PDX establishment and tissue banking.

Timeline

• Start date: 2019-10-16
• Primary completion: 2025-12-31
• Completion: 2026-12-31
• First posted: 2021-01-26
• Last updated: 2024-08-22

Locations

1 site across 1 country: Hong Kong