Trials / Withdrawn
WithdrawnNCT04723589
Restoration of Endothelial Integrity in Patients With COVID-19 (RELIC)
- Status
- Withdrawn
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 0 (actual)
- Sponsor
- University of Alabama at Birmingham · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is a pilot study designed to demonstrate the feasibility of conducting a larger study of standard plasma therapy in COVID-19 patients.
Detailed description
This is a randomized trial in hospitalized COVID-19-positive patients. This trial compares standard care to standard care plus an infusion of non-convalescent thawed plasma. Blood will be collected from all participants at eight timepoints, and clinical data will be collected for 30 days or until discharge/death.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Thawed plasma | Plasma not labeled "convalescent plasma" is presumed to be free of COVID antibodies, but is not tested for antibodies. To ensure that we are using antibody-free plasma, we will test each unit of plasma with a quick COVID test before it is utilized in this study. |
Timeline
- Start date
- 2021-04-30
- Primary completion
- 2021-04-30
- Completion
- 2021-04-30
- First posted
- 2021-01-25
- Last updated
- 2021-06-30
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT04723589. Inclusion in this directory is not an endorsement.