NCT04720209

Taking AIM at Breast Cancer

Taking AIM at Breast Cancer: Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer Survivors

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 102 (actual)
• Sponsor: Dana-Farber Cancer Institute · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research is to determine whether a 16-week exercise program for individuals with breast cancer and have completed treatment (i.e., surgery, chemotherapy, or radiation) for breast cancer will decrease inflammation in fat tissue.

Detailed description

This study is about using different types of exercise to reduce inflammation in fat tissue in an effort to minimize the risk of cancer recurrence related to being overweight or obese. The investigators hope to learn whether participating in a specific exercise program can cause inflammation in the fat tissue to decrease. The names of the study interventions involved in this study are: * Circuit-style aerobic and resistance exercise (CARE) * Traditional aerobic and resistance exercise (TARE) The research study procedures include screening for eligibility, and study treatment including evaluations and follow up visits. The study treatment will be for 4 months and participants will followed for 8 months. The total time for participation in this study will be about 12 months. It is expected that about 300 people will take part in this research study.

Conditions

• Breast Cancer
• Breast Cancer Stage I
• Breast Cancer Stage II
• Breast Cancer Stage III

Interventions

Type	Name	Description
OTHER	CARE	CARE is a 16-week, supervised, periodized AE and RE program performed in a circuit fashion 3 days/week on-site
OTHER	TARE	TARE is a 16- week, supervised AE and RE program consisting of three sessions per week on-site
OTHER	Home-Based Stretching	This group will perform a home-based program of the same stretches utilized in the CARE and TARE groups.

Timeline

• Start date: 2021-08-13
• Primary completion: 2026-08-31
• Completion: 2026-09-15
• First posted: 2021-01-22
• Last updated: 2025-09-23

Locations

2 sites across 1 country: United States