Clinical Trials Directory

Trials / Completed

CompletedNCT04719832

Placebo-controlled Efficacy and Safety Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype

A 52-week, Randomised, Double-blind, Placebo-controlled, Parallel-group, Multi-centre Study of the Efficacy and Safety of GSK3511294 Adjunctive Therapy in Adult and Adolescent Participants With Severe Uncontrolled Asthma With an Eosinophilic Phenotype

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
395 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

This is a multi-center, randomized, placebo-controlled, double-blind, parallel group study that aims to assess the efficacy and safety of GSK3511294 (Depemokimab) in participants with severe uncontrolled asthma with an eosinophilic phenotype

Conditions

Interventions

TypeNameDescription
BIOLOGICALGSK3511294 (Depemokimab)GSK3511294 (Depemokimab) will be administered using a pre-filled syringe.
DRUGPlaceboMatching placebo will be administered as a normal saline using a pre-filled syringe.

Timeline

Start date
2021-03-17
Primary completion
2023-11-21
Completion
2023-11-21
First posted
2021-01-22
Last updated
2024-12-17
Results posted
2024-12-17

Locations

123 sites across 12 countries: United States, Canada, China, Czechia, France, Germany, Ireland, Italy, Poland, Russia, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT04719832. Inclusion in this directory is not an endorsement.