Clinical Trials Directory

Trials / Completed

CompletedNCT04717466

Brain Changes in Psoriasis After Secukinumab Treatment

Brain Morphological Changes Accompanied by Effective Biologic Treatments for Psoriasis and Their Associations With the Improvement of Well-being, Itch, and Pain

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
20 (actual)
Sponsor
University of Miami · Academic / Other
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to assess the effect of a biologic drug targeting the Interleukin (IL)-17 pathway (secukinumab) on brain plasticity and examine whether the plastic changes correlate with the improvement of perception of well-being, itch, and pain in participants with psoriasis.

Conditions

Interventions

TypeNameDescription
BIOLOGICALSecukinumab300mg subcutaneous injection

Timeline

Start date
2021-06-29
Primary completion
2024-05-16
Completion
2025-03-04
First posted
2021-01-22
Last updated
2025-06-05
Results posted
2025-06-05

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04717466. Inclusion in this directory is not an endorsement.