NCT04715178

Beat Childhood Cancer Specimen Banking and Data Registry

Specimen Banking With Clinical and Genomic Data Registry With the Establishment of Tumor Models for Pediatric Cancers

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Giselle Sholler · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

This is an observational data registry study of pediatric cancer patients at participating Beat Childhood Cancer Consortium sites involving specimen banking and data collection.

Detailed description

This observational registry and banking study is being performed on a large cohort of subjects who have received molecular testing to better understand the relationship between genomic and molecular information and clinical outcomes, and to enable timely and informed treatment decisions by physicians for their cancers. We hypothesize that large gene panels, sequencing (DNA/RNA), and epigenetics of tumors can identify molecular aberrations that can be leveraged to offer more effective treatment. Findings may highlight additional areas of research required to better understand the molecular underpinnings of the relationship between molecular abnormalities and disease. Banked specimens and the creation of tumor cell lines and xenograft models will facilitate further advancement of this research.

Conditions

• Pediatric Cancer
• Survivorship

Interventions

Type	Name	Description
OTHER	No intervention- registry only	No intervention- registry only

Timeline

• Start date: 2021-02-02
• Primary completion: 2031-01-01
• Completion: 2032-01-01
• First posted: 2021-01-20
• Last updated: 2026-02-03

Locations

18 sites across 1 country: United States