NCT04713423

Oral and Perioral Herpes Simplex Virus Infection Type I in a Five-month-old Infant: A Case Report

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1 (actual)
• Sponsor: Princess Nourah Bint Abdulrahman University · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

A five-month-old healthy girl who presented with painful herpetic gingivostomatitis and perioral vesicles.

Detailed description

The investigators present the case of a five-month-old healthy girl who presented with painful herpetic gingivostomatitis and perioral vesicles. The investigators discuss the pathophysiology of primary herpes simplex virus infection and the effect of maternal antibodies on the infant's immune system. In addition, the investigators explain the diagnosis, management, and prognosis of herpes simplex virus infection in young infants.

Conditions

• Herpes Simplex Virus Infection

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Diagnosis and treatment of the case	The infant was transferred to a hospital for better management of her infection. She was immediately started on intravenous acyclovir (20 mg/kg/6 h/5 d) while acetaminophen suppositories (80 mg/8 h/5 d) were given to lower her body temperature. In addition, other palliative drugs, such as diphenhydramine syrup (12.5 mg/5 mL, 2.5 mL orally) once-a-night for five days, were given to ease the effort of drinking and to aid in achieving good sleep. Upon completion of five days of therapy, the patient showed complete recovery and was subsequently discharged from the hospital free from symptoms.

Timeline

• Start date: 2017-10-19
• Primary completion: 2017-10-19
• Completion: 2017-10-19
• First posted: 2021-01-19
• Last updated: 2021-01-19

Locations

1 site across 1 country: Saudi Arabia