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CompletedNCT04710264

Aurora Test for Patients Treated With Recombinant Gonadotropins

An Observational Cohort Study to Evaluate the Expression Profiles of Oocyte-potency-related Genes in Ovarian Cumulus Cells From Patients Treated by Intracytoplasmic Sperm Injection (ICSI) That Are Treated With Recombinant Gonadotropins

Status
Completed
Phase
Study type
Observational
Enrollment
137 (actual)
Sponsor
Fertiga, Belgium · Industry
Sex
Female
Age
22 Years – 38 Years
Healthy volunteers
Not accepted

Summary

This is an observational study. The main aim is to determine the expression of potential biomarker genes in the cumulus cells isolated from individual oocytes in two patient cohorts: recombinant human Follicle Stimulating Hormone(hFSH) and recombinant hFSH:human Luteinizing Hormone(r-hLH) ratio 2:1. Algorithms from gene combinations will be identified that predict embryo quality and pregnancy outcomes.

Conditions

Interventions

TypeNameDescription
OTHERAURORA-RecExplorative study of cumulus cells gene expression in relation to the patient treatment and oocyte competence.

Timeline

Start date
2021-02-15
Primary completion
2023-12-31
Completion
2025-09-01
First posted
2021-01-14
Last updated
2025-09-08

Locations

1 site across 1 country: Belgium

Source: ClinicalTrials.gov record NCT04710264. Inclusion in this directory is not an endorsement.

Aurora Test for Patients Treated With Recombinant Gonadotropins (NCT04710264) · Clinical Trials Directory