NCT04707170

MRI Exploration of Meningeal Inflammatory Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 302 (actual)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Patients who have agreed to participate in the study will complete the MRI protocol as part of routine care, to which two additional sequences of 6 minutes duration will be added. The MRI of routine care includes at least the following sequences: * 3D T1 TFE 1.0 isotropic (2 minutes) * T2 TSE (2 minutes) * 3D FLAIR pre-injection (opt) (3 minutes) * 3D FLAIR post-injection (3 minutes) As part of the research, the following sequences will be acquired: * FABIR pre-injection (3 minutes) * FABIR post-injection (3 minutes) Patients hospitalized for a foreseeable duration of at least 24 hours will be offered participation in the longitudinal tab of the study, for which four non-injected MRI examinations will be performed. The examinations will be carried out remotely from the injected MRI (1h, 2h, 12h-15h, 24h-36h). These exams dedicated to research will include the following sequences for a maximum of 8 minutes: * 3D T1 TFE 1.0 isotropic (2 minutes) * 3D FLAIR (3 minutes) * FABIR (3 minutes)

Conditions

• MRI

Interventions

Type	Name	Description
DEVICE	MRI with gadolinium injection	Patients presenting for imaging for whom an MRI examination with gadolinium injection has been prescribed and who meet the inclusion and non-inclusion criteria will be offered to participate in the study. The patients included, hospitalized at the A. de Rothschild Foundation Hospital for at least 24 hours, may be included in the ancillary study to meet secondary objective number 5.

Timeline

• Start date: 2021-06-16
• Primary completion: 2023-06-16
• Completion: 2023-06-16
• First posted: 2021-01-13
• Last updated: 2023-12-13

Locations

1 site across 1 country: France