Clinical Trials Directory

Trials / Completed

CompletedNCT04706884

NEW MONITORING IN DIFFERENTIAL DIAGNOSIS OF HYPERLACTATHEMIA IN CARDIOPULMONARY BYPASS SURGERY

EFFECT OF CEREBRAL OXYGEN SATURATION ON THE ETIOLOGY OF EARLY POSTOPERATIVE HYPERLACTATEMIA: NEW INDICATION FOR KNOWN MONITORING IN CARDIOPULMONARY BYPASS SURGERY

Status
Completed
Phase
—
Study type
Observational
Enrollment
60 (actual)
Sponsor
Acibadem University · Academic / Other
Sex
All
Age
43 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Objective: The objective of the study was to investigate a reverse correlation between blood lactate levels and rSO2, and distinguish between hypoxic and non-hypoxic hyperlactatemia seen in the early postoperative period.

Detailed description

The objective of the prospective study was to investigate a reverse correlation between blood lactate levels and rSO2, and distinguish between hypoxic and non-hypoxic hyperlactatemia seen in the early postoperative period. Sixty American Society of Anesthesiologists (ASA) II-III patients were included in this study. Perioperative data, including age, weight, body surface area, gender, body temperature, preoperative co-morbidities, intraoperative and postoperative hemodynamic parameters, arterial blood gas analysis (ABG), cardiopulmonary bypass and aortic cross-clamp duration, flow rate, urine output, and blood product and inotropic agent usage, were recorded. Postoperative plasma lactate levels were measured simultaneously with cerebral tissue oxygen saturation (rSO2) in both cerebral hemispheres at 10 different time points.

Conditions

Interventions

TypeNameDescription
DEVICENear infrared spectroscopyThe rSO2 (cerebral oxygen satutation) was continuously monitored by NIRS (Near infrared spectroscopy) with a sensor positioned on the forehead of the patient

Timeline

Start date
2018-03-01
Primary completion
2019-02-01
Completion
2019-03-01
First posted
2021-01-13
Last updated
2021-01-14

Locations

2 sites across 1 country: Turkey (Türkiye)

Regulatory

Source: ClinicalTrials.gov record NCT04706884. Inclusion in this directory is not an endorsement.