NCT04705467

3DUS Imaging of Needles in Gynecological Brachytherapy

A Multi-Modality Comparison of Needle Placement During Gynecological Brachytherapy Procedures

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 35 (estimated)
• Sponsor: Western University, Canada · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Brachytherapy treatment in gynecological cancers is an essential component to delivering adequate doses of radiation to a tumour while sparing normal tissue. Interstitial or intra-cavitary brachytherapy are often needed in advanced or recurrent disease, in cases where intrauterine brachytherapy may not deliver the optimal outcome. Interstitial or intra-cavitary brachytherapy are based on a defined template-and-needle system, and the procedure relies on clinical examination and pre-treatment imaging to guide needle insertion. There is currently no standard image-guided process to help direct needles in the pelvis. We propose using 3D ultrasound to provide real-time imaging for the brachytherapy procedure, which will aid in avoiding needle insertion into pelvic organs and result in optimal dose coverage to the tumour.

Conditions

• Gynecologic Cancer

Interventions

Type	Name	Description
DEVICE	Gynecological brachytherapy	Management of gynecological malignancies is done through brachytherapy treatment, which involves the delivery of radiation via radioactive sources that are placed into or in close proximity to the tumour.

Timeline

• Start date: 2022-10-15
• Primary completion: 2025-10-01
• Completion: 2026-06-01
• First posted: 2021-01-12
• Last updated: 2025-04-13

Locations

1 site across 1 country: Canada