Clinical Trials Directory

Trials / Completed

CompletedNCT04704739

Evaluation of Mass Balance and Absolute Bioavailability of GLPG1205

A Phase 1, Open-label Study to Investigate the Pharmacokinetics and Metabolism of GLPG1205 in Healthy Male Subjects Following Single Intravenous [14C]-GLPG1205 Microtracer and Single Oral [14C]-GLPG1205 Administration

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
12 (actual)
Sponsor
Galapagos NV · Industry
Sex
Male
Age
18 Years – 64 Years
Healthy volunteers
Accepted

Summary

A study in healthy male volunteers to assess how the radiolabelled test medicine is taken up and broken down by the body when given by short infusion into a vein and when given by the mouth in the form of a capsule or tablet.

Conditions

Interventions

TypeNameDescription
DRUGGLPG1205 film-coated tabletsSingle oral dose of GLPG1205
DRUG[14C]-GLPG1205 solution for infusionA 15-minute IV infusion of \[14C\]-GLPG1205
DRUGGLPG1205 capsulesSingle oral dose of GLPG1205 as solid formulation

Timeline

Start date
2021-01-13
Primary completion
2021-03-02
Completion
2021-03-10
First posted
2021-01-12
Last updated
2021-03-25

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT04704739. Inclusion in this directory is not an endorsement.