NCT04699890

Development of Specific Diagnostic Tools for Cardiac Insufficiency With Preserved Ejection Fraction

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 91 (actual)
• Sponsor: University Hospital, Montpellier · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

The MeDIAGSTOLE project aims to develop diagnostic tools for heart failure with preserved ejection fraction (IC / FEp), a pathology that is difficult to diagnose and to manage clinically in the absence of targeted treatment . The IC / FEp concerns the elderly population with comorbidities such as hypertension, obesity, anemia and atrial fibrillation. In the absence of specific biomarkers, clinical diagnosis is based on serum markers of heart failure with reduced ejection fraction (IC / FEr). The identification of new biomarkers, genetic and / or cellular, specific for IC / FEp would be an important innovation.

Conditions

• Heart Failure

Interventions

Type	Name	Description
OTHER	Blood sampling, questionnaires and specific exams	Patients will have additionnal blood samples, answer to self-questionnaires and will performed an electrocardiogram and an echocardiography if not performed in routine care.

Timeline

• Start date: 2022-01-11
• Primary completion: 2025-01-31
• Completion: 2025-01-31
• First posted: 2021-01-07
• Last updated: 2025-09-30

Locations

1 site across 1 country: France