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Active Not RecruitingNCT04696809

A Study of Teclistamab in Japanese Participants With Relapsed or Refractory Multiple Myeloma

A Phase 1/2 Study of JNJ-64007957, a Humanized BCMA * CD3 Bispecific Antibody in Japanese Patients With Relapsed or Refractory Multiple Myeloma

Status
Active Not Recruiting
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
40 (actual)
Sponsor
Janssen Pharmaceutical K.K. · Industry
Sex
All
Age
20 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to evaluate the safety and tolerability in Japanese participants with relapsed or refractory multiple myeloma (RRMM) at the recommended Phase 2 dose (RP2D) identified in Study 64007957MMY1001 (NCT03145181) in Phase 1 part and to evaluate the efficacy of teclistamab at RP2D for Japanese participants in Phase 2 part.

Conditions

Interventions

TypeNameDescription
DRUGTeclistamabTeclistamab will be administered subcutaneously.

Timeline

Start date
2021-02-22
Primary completion
2026-04-22
Completion
2026-04-22
First posted
2021-01-06
Last updated
2026-04-13

Locations

15 sites across 1 country: Japan

Regulatory

Source: ClinicalTrials.gov record NCT04696809. Inclusion in this directory is not an endorsement.