Clinical Trials Directory

Trials / Completed

CompletedNCT04693234

AdvanTIG-202: Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Previously Treated Recurrent or Metastatic Cervical Cancer

Phase 2 Study Investigating Efficacy and Safety of Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody BGB-A1217 in Patients With Previously Treated Recurrent or Metastatic Cervical Cancer

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
178 (actual)
Sponsor
BeiGene · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study tested how well and how safely the drug tislelizumab, given either alone or with another drug called ociperlimab (BGB-A1217), worked in people with cervical cancer that had come back or spread after previous treatments. The study included two groups and took place at multiple medical centers.

Conditions

Interventions

TypeNameDescription
BIOLOGICALTislelizumab200 mg administered intravenously once every 3 weeks on day 1 of each cycle
BIOLOGICALOciperlimab900 mg administered intravenously once every 3 weeks on day 1 of each cycle

Timeline

Start date
2021-02-15
Primary completion
2022-06-16
Completion
2023-08-31
First posted
2021-01-05
Last updated
2025-04-27
Results posted
2025-04-27

Locations

68 sites across 8 countries: Bulgaria, China, Poland, Russia, South Korea, Taiwan, Thailand, Ukraine

Source: ClinicalTrials.gov record NCT04693234. Inclusion in this directory is not an endorsement.