Clinical Trials Directory

Trials / Recruiting

RecruitingNCT04690348

Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
103 (estimated)
Sponsor
Memorial Sloan Kettering Cancer Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to see if Cs-131 brachytherapy is effective in people with recurrent brain cancer who are scheduled to have brain surgery for removal of their tumor(s). The researchers would like to see whether Cs-131 prevents brain tumors from growing back after surgery.The researchers will compare Cs-131 brachytherapy (which occurs during brain surgery) with the usual approach of brain surgery without brachytherapy. The researchers will compare both the effectiveness and safety of the two approaches.

Conditions

Interventions

TypeNameDescription
PROCEDURECraniotomyCraniotomy
RADIATIONCesium-131 brachytherapyIntracavitary Cesium-131 brachytherapy

Timeline

Start date
2020-12-24
Primary completion
2026-12-01
Completion
2026-12-01
First posted
2020-12-30
Last updated
2026-01-13

Locations

6 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04690348. Inclusion in this directory is not an endorsement.