NCT04689243

Low Concentration ALA-PDT in Treatment of Skin Ulcer

Clinical Study of Low Concentration ALA-PDT in Treatment of Skin Ulcer

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (estimated)
• Sponsor: Sichuan Provincial People's Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Skin ulcer is a common disease with complicated etiopathogenes, which makes it hard to be cured. It has been reported that photodynamic therapy (PDT) can be used to treat skin ulcers which were caused by different diseases. However, PDT is an expensive treatment and patients always experience obvious pain during or after the treatment, which hinders the application of PDT in skin ulcer. Our previous study found that PDT using a low concentration of 5-Aminolevulinic acid (ALA) could promote the healing of skin ulcer without obvious adverse reactions, which suggests us that low concentration ALA-PDT might be an efficient and cost effective treatment in skin ulcer. To further investigate the use of low concentration ALA-PDT in skin ulcer, we plan to recruit patients with skin ulcers caused by different diseases, and divide these patients into different groups according to their causes of disease, and then treat them using low concentration ALA-PDT to observe the healing process of skin ulcer. This study could further optimize and promote the use of low concentration ALA-PDT in skin ulcer.

Conditions

• Skin Ulcer
• Photodynamic Therapy

Interventions

Type	Name	Description
PROCEDURE	ALA-PDT	Low concentration ALA-PDT, 3 times a week.
PROCEDURE	red light	red light, 3 times a week.

Timeline

• Start date: 2019-01-01
• Primary completion: 2020-12-26
• Completion: 2020-12-30
• First posted: 2020-12-30
• Last updated: 2020-12-30

Locations

1 site across 1 country: China