NCT04687865

Constitution of a Biobank for Studies Related to Organ Transplantation (Lyon Centaure Biocollection)

Biological Material Bank for Studies Related to Organ Transplantation

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 4,000 (estimated)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

This study aims to constitute a collection of biological materials from in transplant patients and to provide biological materials from transplanted patients in order : i) validate new theory on the cause of allograft loss, ii) develop innovative biomarker for rejection and other transplantation-related conditions (such as BK virus nephropathy, Post-transplant lymphoproliferative disorder ( PTLD) ...)

Conditions

• Organ Transplantation

Interventions

Type	Name	Description
OTHER	Biobank	For each patient included in the study the following samples will be collected at the indicated time points after transplantation: * Serum samples and plasma sample: Day1, Month 1, Month 3, Month 6, Month 12, month 60, month 120 and at the time of each allograft biopsy. * Urines samples: Month 3 and Month 12 and at the time of each allograft biopsy. * Peripheral Blood Mononuclear Cell (PBMC): for each organ allograft biopsy. * Allograft biopsies: systematically at Month 3, and Month 12, and for cause in case of allograft dysfunction.

Timeline

• Start date: 2020-01-08
• Primary completion: 2040-01-08
• Completion: 2040-01-08
• First posted: 2020-12-29
• Last updated: 2025-03-07

Locations

1 site across 1 country: France