NCT04687150

Fecal Microbiota Transplantation and Newly Diagnosed Ulcerative Colitis (UC)

Fecal Microbiota Transplantation in Newly Diagnosed Ulcerative Colitis Patients

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Turku University Hospital · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In this FinUC study we are trying to find out the efficacy and safety of the Fecal microbiota transplantation (FMT) in newly diagnosed active ulcerative colitis patients. The study group with newly diagnosed active ulcerative colitis receive an FMT via colonoscopy from a tested general donor, frozen and thawed from a fecal bank at week 0 and at week 4 as an enema at the study nurse´s visit. The control group will be given colored water. The main aim of the FinUC study is to determine how the FMT change of the gut microbiota composition in newly diagnosed active ulcerative colitis patients. The other aim is to determine efficacy and mechanisms of fecal microbiota transplantation.

Conditions

• Ulcerative Colitis

Interventions

Type	Name	Description
OTHER	Fecal microbiota transplantation	Fecal microbiota transplantation from a tested general donor, frozen and thawed from a fecal bank
OTHER	Colored water	Colored water (placebo)

Timeline

• Start date: 2021-01-01
• Primary completion: 2023-12-01
• Completion: 2024-03-01
• First posted: 2020-12-29
• Last updated: 2022-10-19

Locations

1 site across 1 country: Finland